T. Mukherjee

Nuclear localization of HD-Zip IV transcription factor GLABRA2 is driven byImportin α

This study identifies a conserved nuclear localization sequence in GLABRA2 that mediates its nuclear import via Importin, essential for epidermal cell differentiation in Arabidopsis.

HIV-differentiated metabolite N-Acetyl-L-Alanine dysregulates human natural killer cell responses to Mycobacterium tuberculosis infection

The paper identifies N-Acetyl-L-Alanine as a metabolite dysregulated by HIV that inhibits NK cell responses to Mycobacterium tuberculosis infection.

START domain mediates Arabidopsis GLABRA2 transcription factor dimerization and turnover independently of homeodomain DNA binding

This study investigates the role of the START domain in GLABRA2 dimerization and protein turnover, showing it is independent of DNA binding and essential for stability.

Arabidopsis PROTODERMAL FACTOR2 binds lysophosphatidylcholines and transcriptionally regulates phospholipid metabolism

This study shows that PDF2, an HD-Zip IV TF, binds lysophosphatidylcholines via its START domain and regulates phospholipid metabolism in response to phosphate availability.

Telmisartan restricts Chikungunya virus infection in vitro and in vivo through the AT1/ PPAR-γ/MAPKs pathways

This study shows Telmisartan reduces Chikungunya virus infection in vitro and in vivo by modulating host pathways including AT1/PPAR-γ/MAPKs.

Elevation of TRPV1 expression on T cells during experimental immunosuppression

This study shows TRPV1 expression increases during T cell immunosuppression and contributes to elevated intracellular calcium levels, similar to immune activation.

G9a and Sirtuin6 epigenetically modulate host cholesterol accumulation to facilitate mycobacterial survival

This study identifies G9a and Sirt6 as epigenetic regulators that modulate host cholesterol accumulation, supporting Mycobacterium tuberculosis survival.

Understanding distribution and occupancy of Himalayan Monal in Uttarkashi district, Uttarakhand

This study estimates the occupancy and abundance of Himalayan Monal in Uttarkashi district using camera traps and sign surveys, finding higher abundance outside protected areas.

Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity

The paper shows that bone marrow adipocyte whitening during obesity drives the increase of invasive Ly6Chigh monocytes, preceding adipose tissue macrophage expansion.

An epithelial Nfkb2 pathway exacerbates intestinal inflammation by supplementing latent RelA dimers to the canonical NF-κB module

The paper shows that noncanonical NF-κB signaling in intestinal epithelial cells enhances latent RelA dimers, amplifying canonical NF-κB activity and exacerbating intestinal inflammation in IBD.

New insights on species divergence in red panda

The paper identifies the Siang river as a potential boundary for divergence between two red panda species using Bayesian phylogeny and MJ network analysis.