Author

K. Papavinasasundaram

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

C. M. Sassetti· 3 shared A. Bandekar· 1 shared A. J. C. Steyn· 1 shared A. J. Olive· 1 shared C. Baer· 1 shared C. C. Boutte· 1 shared D. Mott· 1 shared E. Jaecklein· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersMicrobiology

C. M. Sassetti

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Author profile →

3 papers

Recent·Most cited

High bacillary burden and the ESX-1 type VII secretion system promote MHC class I presentation by Mycobacterium tuberculosis infected macrophages to CD8 T-cells

D. Mott, J. Yang, C. Baer, K. Papavinasasundaram, C. M. Sassetti, S. M. Behar

The paper shows high Mtb burden in macrophages leads to cell death and cross-presentation of TB10.4 antigen to CD8 T-cells via the ESX-1 system, promoting immune response but potentially worsening immunopathology.

bioRxiv · Oct 20, 2022 · PreprintImmunology

Phosphorylation on PstP regulates cell wall metabolism and antibiotic tolerance in Mycobacterium smegmatis

F. Shamma, K. Papavinasasundaram, S. Y. Quintanilla, A. Bandekar, C. M. Sassetti, C. C. Boutte

This study shows that phosphorylation of PstP affects cell wall metabolism and antibiotic tolerance in Mycobacterium smegmatis by regulating peptidoglycan and mycolic acid metabolism during growth and stasis.

bioRxiv · Oct 26, 2020Microbiology

Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase

Y. Cai, E. Jaecklein, J. Mackenzie, K. Papavinasasundaram, A. J. Olive, X. Chen, A. J. C. Steyn, C. M. Sassetti

This study shows that Mycobacterium tuberculosis relies on cytochrome bd oxidase to resist the adaptive immune response, particularly under acidic conditions in macrophages.

bioRxiv · Aug 21, 2020Microbiology