Author

K. S. Kao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:protein structure· 1

Frequent Co-Authors

J. V. Ravetch· 2 shared R. Yamin· 2 shared A. C. Le· 1 shared A. Chen· 1 shared A. Chhabra· 1 shared A. Gupta· 1 shared B. George· 1 shared C. Burnett· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

J. V. Ravetch

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanism of glycoform specificity and protection against antibody dependent enhancement by an anti-afucosylated IgG nanobody

A. Gupta, K. S. Kao, R. Yamin, D. A. Oren, Y. Golgur, J. Du, P. Lollar, E. Sundberg, J. V. Ravetch

This paper presents the X-ray structure of a nanobody that binds afucosylated IgG1 Fc and disrupts pathogenic interactions, rescuing mice in a dengue model.

bioRxiv · Jan 23, 2023 · PreprintImmunology

Human FcγRIIIa activation on splenic macrophages drives the in vivo pathogenesis of dengue disease

R. Yamin, K. S. Kao, M. R. MacDonald, T. Cantaert, C. M. Rice, J. V. Ravetch, S. Bournazos

This study shows that anti-DENV IgG antibodies drive dengue pathogenesis via FcγRIIIa on splenic macrophages, leading to inflammation and mortality.

bioRxiv · Nov 2, 2022 · PreprintImmunology

Enabling MHC-mismatched hematopoietic stem cell transplants and organ graft tolerance without chemotherapy or radiation

B. George, K. S. Kao, A. Chen, A. C. Le, A. Chhabra, C. Burnett, K. M. Loh, J. A. Shizuru, I. Weissman

This study develops six monoclonal antibodies to deplete immune cells in mice, enabling MHC-mismatched HSC transplants without chemotherapy or radiation, leading to immune tolerance.

bioRxiv · Jan 21, 2019 · PreprintImmunology