Author

H. Horn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 3 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:drug response / drug discovery· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Assay:whole-exome sequencing· 2

Frequent Co-Authors

J. Gescher· 4 shared K. Lage· 2 shared M. Hackbarth· 2 shared M. Wagner· 2 shared A. Doan· 1 shared A. Fragoulis· 1 shared A. Gupta· 1 shared A. Kamburov· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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4 shared papersMicrobiology

J. Gescher

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Oxic microbial electrosynthesis can be more energy efficient for biomass production than knallgas or photosynthesis based processes

L. Rominger, M. Hackbarth, T. Jung, M. Scherzinger, H. Horn, M. Kaltschmitt, J. Gescher

This study demonstrates that oxic microbial electrosynthesis can achieve higher energy efficiency for biomass production than traditional gas fermentation or photosynthesis-based processes.

bioRxiv · May 24, 2023 · PreprintBioengineering

A scalable, Rotating Disc Bioelectrochemical Reactor (RDBER) suitable for the cultivation of both cathodic and anodic biofilms

M. Hackbarth, J. Gescher, H. Horn, J. E. Reiner

This paper describes a scalable rotating disc bioelectrochemical reactor for cultivating cathodic and anodic biofilms, demonstrating its use for microbial electrosynthesis and microbial electrolysis with high current densities and hydrogen production.

bioRxiv · Sep 12, 2022Microbiology

Design, immunogenicity and efficacy of a Pan-SARS-CoV-2 synthetic DNA vaccine

C. C. Reed, K. Schultheis, V. M. Andrade, R. Kalia, J. Tur, B. Schouest, D. Elwood, J. N. Walters, I. Maricic, A. Doan, M. Vazquez, Z. Eblimit, P. Pezzoli, D. Amante, M. Porto, , K. E. Broderick

This study designs and tests a DNA vaccine, INO-4802, which induces broad immunity against multiple SARS-CoV-2 variants in animal models.

bioRxiv · May 11, 2021 · PreprintImmunology

Extracellular riboflavin induces anaerobic biofilm formation in Shewanella oneidensis

M. Edel, G. Sturm, K. Sturm-Richter, M. Wagner, J. Novion Ducassou, Y. Coute, H. Horn, J. Gescher

This study shows that riboflavin acts as a quorum sensing molecule in Shewanella oneidensis, triggering anaerobic biofilm formation at a specific threshold concentration.

bioRxiv · Feb 19, 2021Microbiology

Using protein interaction networks to identify cancer dependencies from tumor genome data

H. Horn, C. Fagre, A. Gupta, K. Tsafou, N. Fornelos, J. T. Neal, K. Lage

This paper develops an algorithm to predict cancer dependencies from tumor genomes by analyzing protein interaction networks and validates its predictions using CRISPR screens.

bioRxiv · Aug 27, 2020 · PreprintCancer Biology

Macrophages protect against loss of adipose tissue during cancer cachexia

M. Erdem, D. Moeckel, S. Jumpertz, C. John, A. Fragoulis, I. Rudolph, J. Wulfmeier, J. Springer, H. Horn, M. Koch, G. Lurje, T. Lammers, G. van der Kroft, F. Gremse, T. Cramer

This study shows that defective myeloid cell-mediated inflammation enhances cachexia in HCC mice, suggesting macrophages protect against fat loss in cancer cachexia.

bioRxiv · Sep 27, 2018Cancer Biology

Expanding discovery from cancer genomes by integrating protein network analyses with in vivo tumorigenesis assays

H. Horn, M. S. Lawrence, C. R. Chouinard, Y. Shrestha, J. Xin Hu, E. Worstell, E. Shea, N. Ilic, E. Kim, A. Kamburov, A. Kashani, J. D. Campbell, W. C. Hahn, J. S. Boehm, G. Getz, K. Lage

The paper develops a method to identify new cancer genes by integrating protein network analysis with in vivo tumorigenesis assays, finding 62 new candidates and validating two in patient data.

bioRxiv · Oct 30, 2017Cancer Biology

Machine-assisted cultivation and analysis of biofilms

S. H. Hansen, T. Kabbeck, C. P. Radtke, S. Krause, E. Krolitzki, T. Peschke, J. Gasmi, K. S. Rabe, M. Wagner, H. Horn, J. Hubbuch, J. Gescher, C. M. Niemeyer

The paper introduces a microfluidic platform for machine-assisted cultivation and analysis of biofilms, demonstrating its ability to monitor biofilm dynamics and microbial separation.

bioRxiv · Oct 28, 2017Microbiology