Author

F. Tamzalit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell-cell communication· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1

Frequent Co-Authors

M. Huse· 3 shared L. C. Kam· 2 shared M. S. Wang· 2 shared V. Boyko· 2 shared W. Jin· 2 shared A. H. Settle· 1 shared A. Kepecs· 1 shared B. Y. Winer· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

M. Huse

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Author profile →

3 papers

Recent·Most cited

Topographical analysis of immune cell interactions reveals a biomechanical signature for immune cytolysis

M. de Jesus, A. H. Settle, D. Vorselen, T. K. Gaetjens, M. Galiano, Y. Y. Wong, T.-M. Fu, E. Santosa, B. Y. Winer, F. Tamzalit, M. S. Wang, Z. Bao, J. C. Sun, P. Shah, J. A. Theriot, , M. Huse

The paper analyzes immune cell interactions using traction force microscopy to identify biomechanical features associated with cytotoxic T cell activity.

bioRxiv · Apr 16, 2023 · PreprintImmunology

Centrioles control the capacity, but not the specificity, of cytotoxic T cell killing

F. Tamzalit, D. Tran, W. Jin, V. Boyko, H. Bazzi, A. Kepecs, L. C. Kam, K. V. Anderson, M. Huse

This study shows that centrioles affect the capacity but not the specificity of cytotoxic T cell killing by impacting granule biogenesis and actin remodeling, not granule polarization.

bioRxiv · Jul 22, 2019Immunology

Interfacial actin protrusions mechanically potentiate killing by cytotoxic T cells

F. Tamzalit, M. S. Wang, W. Jin, V. Boyko, J. M. Heddleston, C. T. Black, L. C. Kam, M. Huse

Cytotoxic T cells use actin-rich protrusions at immunological synapses to enhance perforin and granzyme-mediated killing of target cells.

bioRxiv · Oct 14, 2018Immunology