Author

D. Kawauchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:scRNA-seq· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

A. Korshunov· 3 shared K. Okonechnikov· 3 shared S. M. Pfister· 3 shared B. A. Orr· 2 shared B. Statz· 2 shared D. T. W. Jones· 2 shared K. W. Pajtler· 2 shared L. M. Kutscher· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Korshunov

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Author profile →

5 papers

Recent·Most cited

Meis1 isoform diversity orchestrates neural progenitor differentiation by regulating ATOH1 degradation at distinct subcellular compartments

T. Owa, T. Adachi, R. Shiraishi, K. Ichijo, K. Ji, M. Mizuno, K. Suyama, K. Nishitani, I. Hasegawa, M. Sone, D. Kawauchi, T. Nishioka, S. Taya, Y. Suzuki, K. Kaibuchi, , M. Hoshino

The paper identifies functionally antagonistic Meis1 isoforms that regulate ATOH1 degradation through distinct subcellular localization and E3 ligase interactions, affecting neural progenitor differentiation.

PLOS Biology · Jul 13, 2026Peer-reviewedCell Biology

Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage

D. R. Ghasemi, K. Okonechnikov, A. Rademacher, S. Tirier, K. K. Maass, H. Schumacher, J. Sundheimer, B. Statz, A. S. Rifaioglu, K. Bauer, S. Schumacher, M. Bortolomeazzi, F. Giangaspero, K. J. Ernst, J. Saez-Rodriguez, , K. W. Pajtler

The paper uses single-cell transcriptomics to show how two compartments in medulloblastoma are connected through a migrating precursor stage, revealing spatial and developmental links between proliferating and differentiated tumor cells.

Nature Communications · Jan 8, 2024Peer-reviewedCancer Biology

Glioblastoma Mesenchymal Transition and Invasion are Dependent on a NF-κB/BRD2 Chromatin Complex

r. vadla, S. Miki, B. Taylor, D. Kawauchi, B. M. Jones, N. Nathwani, P. Pham, J. Tsang, D. A. Nathanson, F. B. Furnari

This study identifies the PTEN-NF-κB-BRD2 pathway as critical for glioblastoma mesenchymal transition and invasion, suggesting BET-BD2 inhibitors as a therapeutic strategy.

bioRxiv · Jul 3, 2023 · PreprintCancer Biology

Mapping pediatric brain tumors to their origins in the developing cerebellum

K. Okonechnikov, P. Joshi, M. Sepp, K. Leiss, I. Sarropoulos, F. Murat, M. Sill, P. Beck, K. C.-H. Chan, A. Korshunov, F. Sahm, M. Y. Deng, D. Sturm, J. DeSisto, A. M. Donson, , S. M. Pfister

The paper maps the cellular origins of three common pediatric brain tumors using a single-nucleus atlas and transcriptome data, identifying lineage-specific origins and potential therapeutic targets.

bioRxiv · Dec 19, 2021Cancer Biology

Functional loss of a non-canonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation

L. M. Kutscher, K. Okonechnikov, N. V. Batora, J. Clark, P. B. G. Silva, M. Vouri, S. van Rijn, L. Sieber, B. Statz, M. D. Gearhart, N. Mack, B. A. Orr, A. Korshunov, A. L. Mercier, O. Ayrault, , D. Kawauchi

This study shows that loss of BCOR in SHH-medulloblastoma accelerates tumor formation by disrupting the BCOR-PRC1.1 complex and increasing Igf2 expression.

bioRxiv · Feb 6, 2020Cancer Biology