Author

K. Wakae

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

M. Muramatsu· 3 shared A. Murayama· 2 shared H. H. Aly· 2 shared K. Chayama· 2 shared K. Shimotohno· 2 shared M. Sugiyama· 2 shared M. Tsuge· 2 shared T. Kato· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

M. Muramatsu

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Author profile →

3 papers

Recent·Most cited

Evasion of APOBEC1-mediated Intrinsic Immunity by a Herpesvirus Uracil DNA Glycosylase Is a Determinant of Viral Encephalitis

A. Kato, H. Harima, Y. Tsunekawa, M. Igarashi, K. Kitamura, K. Wakae, H. Kozuka-Hata, M. Oyama, M. Watanabe, K. Takeshima, Y. Maruzuru, N. Koyanagi, T. Okada, M. Muramatsu, Y. Kawaguchi

This study shows that HSV-1's vUNG enzyme evades APOBEC1 immunity by preventing DNA editing, leading to more severe encephalitis in mice.

bioRxiv · Jun 22, 2023 · PreprintMicrobiology

The kinesin KIF4 mediates HBV/HDV entry through regulation of surface NTCP localization and can be targeted by RXR agonists in vitro.

S. A. Gad, M. Sugiyama, M. Tsuge, K. Wakae, K. Fukano, M. Oshima, C. Sureau, N. Watanabe, T. Kato, A. Murayama, Y. Li, I. Shoji, K. Shimotohno, K. Chayama, M. Muramatsu, , H. H. Aly

This paper identifies KIF4 as a critical regulator of NTCP surface localization for HBV/HDV entry and shows RXR agonists can suppress KIF4 to inhibit viral infection.

bioRxiv · Sep 29, 2021Microbiology

MafF is an antiviral host factor that suppresses transcription from Hepatitis B Virus core promoter

M. K. Ibrahim, T. H. Abdelhafez, J. S. Takeuchi, K. Wakae, M. Sugiyama, M. Tsuge, M. Ito, K. Watashi, M. El Kassas, T. Kato, A. Murayama, T. Suzuki, K. Chayama, K. Shimotohno, M. Muramatsu, , T. Wakita

This study identifies MafF as an antiviral host factor that suppresses HBV core promoter transcription, contributing to host defense against HBV infection.

bioRxiv · Jul 29, 2020Microbiology