Author

Y. Maruzuru

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Assay:proteomics· 3 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

A. Kato· 4 shared K. Takeshima· 4 shared N. Koyanagi· 4 shared Y. Kawaguchi· 4 shared M. Nobe· 3 shared A. Fukui· 1 shared F. Maeda· 1 shared H. Harima· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersMicrobiology

A. Kato

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Regulatory Mimicry of Cyclin-Dependent Kinases by Conserved Herpesvirus Protein Kinases

N. Koyanagi, K. Hengphasatporn, A. Kato, M. Nobe, K. Takeshima, Y. Maruzuru, K. Maenaka, Y. Shigeta, Y. Kawaguchi

This study identifies herpesvirus protein kinases that mimic CDK regulation, showing their role in viral replication and pathogenicity.

bioRxiv · Oct 18, 2023Microbiology

Evasion of APOBEC1-mediated Intrinsic Immunity by a Herpesvirus Uracil DNA Glycosylase Is a Determinant of Viral Encephalitis

A. Kato, H. Harima, Y. Tsunekawa, M. Igarashi, K. Kitamura, K. Wakae, H. Kozuka-Hata, M. Oyama, M. Watanabe, K. Takeshima, Y. Maruzuru, N. Koyanagi, T. Okada, M. Muramatsu, Y. Kawaguchi

This study shows that HSV-1's vUNG enzyme evades APOBEC1 immunity by preventing DNA editing, leading to more severe encephalitis in mice.

bioRxiv · Jun 22, 2023 · PreprintMicrobiology

Direct Relationship between Protein Expression and Progeny Yield of Herpes Simplex Virus 1 Unveils a Rate-limiting Step for Virus Production

M. Nobe, Y. Maruzuru, K. Takeshima, F. Maeda, H. Kusano, R. Yoshimura, T. Nishiyama, H. Park, Y. Kozaki, S. Iwami, N. Koyanagi, A. Kato, T. Natsume, S. Adachi, Y. Kawaguchi

This study identifies a direct relationship between viral protein expression and progeny yield in herpes simplex virus 1, revealing DNA cleavage/packaging as a rate-limiting step for virus production.

bioRxiv · Jun 7, 2023 · PreprintMicrobiology

Dual Impacts of a Glycan Shield on the Envelope Glycoprotein B of HSV-1: Evasion from Human Antibodies In Vivo and Neurovirulence

A. Fukui, Y. Maruzuru, S. Ohno, M. Nobe, S. Iwata, K. Takeshima, N. Koyanagi, A. Kato, S. Kitazume, Y. Yamaguchi, Y. Kawaguchi

This study identifies an N-glycan shield on HSV-1 gB that mediates evasion from human antibodies in vivo and contributes to neurovirulence.

bioRxiv · Dec 12, 2022Microbiology