3D matrix adhesion composition facilitates nuclear force coupling to drive invasive cell migration
D. Newman, L. Young, T. Waring, L. Brown, K. Wolanska, E. MacDonald, A. Charles-Orszag, P. Caswell, T. Sakuma, T. Yamamoto, L. M. Machesky, M. Morgan, T. N. Zech
This study identifies a 3D matrix adhesion complex involving β-PIX and Myo18A that drives invasive cell migration by coupling nuclear force transmission to protrusion dynamics.
bioRxiv · May 17, 2021 · PreprintCell Biology