K.-W. Liu

Aspergillus fumigatus cytochrome c impacts conidial survival during sterilizing immunity

This study shows that loss of cytochrome c in Aspergillus fumigatus reduces susceptibility to ROS-induced cell death and host leukocyte killing.

Post-Influenza Environment Reduces Aspergillus fumigatus Conidia Clearance and Facilitates Invasive Aspergillosis In Vivo

This study shows that influenza virus infection impairs neutrophil and monocyte function, reducing Aspergillus fumigatus conidia clearance and increasing invasive aspergillosis in mice.

Strain specific persistence in the murine lung of Aspergillus fumigatus conidia causes an Allergic Broncho-Pulmonary Aspergillosis-like disease phenotype

This study identifies an A. fumigatus strain, W72310, that persists in the mouse lung and causes ABPA-like disease without significant hyphal growth.

MDA5 is an essential vita-PAMP sensor necessary for host resistance against Aspergillus fumigatus

This study shows MDA5 is essential for host resistance against Aspergillus fumigatus through type I and III interferon signaling and antifungal neutrophil activity.

Cell size-dependent regulation of Wee1 localization by Cdr2 cortical nodes

This study shows how cell growth inhibits fission yeast Wee1 through dynamic bursts of its localization to cortical nodes containing inhibitory kinases.