Author

Kanako Komatsu

National Center of Neurology and Psychiatry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:database / resource· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2

Frequent Co-Authors

Kaoru YagitaiD· 3 shared Kayo Nishitani· 3 shared Kazumi ShimaokaiD· 3 shared Keiya IijimaiD· 3 shared Kumiko Murayama· 3 shared Masaki IwasakiiD· 3 shared Masaki TakaoiD· 3 shared Mikio HoshinoiD· 3 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Kaoru YagitaORCID

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Author profile →

3 papers

Recent·Most cited

Spatial transcriptomics identifies L6 corticothalamic and L6b subplate-like heterotopic neurons in an epileptogenic SLC35A2-associated brain malformation.

Nao K N Tabe, Satoshi Miyashita, Kaoru Yagita, Keiya Iijima, Kazumi Shimaoka, Ai Hosaka, Sota Okumiya, Kayo Nishitani, Kanako Komatsu, Emi Usukura, Kumiko Murayama, Terunori Sano, Masaki Takao, Masaki Iwasaki, Mikio Hoshino

The paper identifies molecular features of WM heterotopic neurons in MOGHE using spatial transcriptomics and supports findings with immunohistochemistry and a mouse model.

bioRxiv · Sep 8, 2026 · PreprintNeuroscience

Comprehensive transcriptomic and proteomic profiling of mTOR-related epilepsy

Kaiyuan Ji, Satoshi Miyashita, Keiya Iijima, Kaoru Yagita, Tomoo Owa, Kazumi Shimaoka, Nao K N Tabe, Minami Mizuno, Ai Hosaka, Kayo Nishitani, Kumiko Murayama, Kanako Komatsu, Masaki Sone, Terunori Sano, Shinichiro Taya, , Mikio Hoshino

The paper integrates transcriptomic and proteomic data from mTOR-related epilepsy patients to identify impaired oxidative phosphorylation as a molecular hallmark.

bioRxiv · Mar 11, 2026 · PreprintNeuroscience

Single-cell-resolved spatial multi-omics identifies mTOR-driven neuronal and astroglial pathogenicity underlying epileptogenic focal cortical dysplasia

Kazumi Shimaoka, Satoshi Miyashita, Keiya Iijima, Kaoru Yagita, Nao K N Tabe, Koichi Hashizume, Nariko Arimura, Shuyu He, Minami Mizuno, Kayo Nishitani, Kanako Komatsu, Kumiko Murayama, Masaki Sone, Emi Usukura, Terunori Sano, , Mikio Hoshino

The paper uses spatial multi-omics to analyze FCDIIb tissue, revealing cell-type-specific effects of mTOR mutations on metabolic and immune pathways in drug-resistant epilepsy.

bioRxiv · Jan 23, 2026 · PreprintNeuroscience