Keiya Iijima

Spatial transcriptomics identifies L6 corticothalamic and L6b subplate-like heterotopic neurons in an epileptogenic SLC35A2-associated brain malformation.

The paper identifies molecular features of WM heterotopic neurons in MOGHE using spatial transcriptomics and supports findings with immunohistochemistry and a mouse model.

Comprehensive transcriptomic and proteomic profiling of mTOR-related epilepsy

The paper integrates transcriptomic and proteomic data from mTOR-related epilepsy patients to identify impaired oxidative phosphorylation as a molecular hallmark.

Single-cell-resolved spatial multi-omics identifies mTOR-driven neuronal and astroglial pathogenicity underlying epileptogenic focal cortical dysplasia

The paper uses spatial multi-omics to analyze FCDIIb tissue, revealing cell-type-specific effects of mTOR mutations on metabolic and immune pathways in drug-resistant epilepsy.

Visualization of functional and effective connectivity underlying auditory descriptive naming

The paper visualizes functional and effective connectivity in white matter networks during auditory descriptive naming tasks, showing how phrase order influences neural dynamics.