Author

Kanami Moriya

Hokkaido University

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Biology Disciplines

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Molecular Biology· 1

Frequent Co-Authors

Ai FujimotoiD· 1 shared Akira KitamuraiD· 1 shared Ayumi Kurata· 1 shared Kazuho Takahashi· 1 shared Kotetsu Sasaki· 1 shared Laura C. BottiD· 1 shared Masataka KinjoiD· 1 shared Rei KawashimaiD· 1 shared

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2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Ai FujimotoORCID

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1 paper

Recent·Most cited

Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity

Akira Kitamura, Ai Fujimoto, Rei Kawashima, Yidan Lyu, Kotetsu Sasaki, Y. Hamada, Kanami Moriya, Ayumi Kurata, Kazuho Takahashi, Renée M. Brielmann, Laura C. Bott, Richard I. Morimoto, Masataka Kinjo

This study shows that truncated RRM in TDP-43 CTFs causes structural changes in IDR, leading to toxic hetero-oligomers and cell-nonautonomous toxicity in nematodes.

Communications Biology · Jun 20, 2024Peer-reviewedMolecular Biology