Author

Ai Fujimoto

Hokkaido UniversityORCID 0000-0003-3572-4001Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Akira KitamuraiD· 2 shared Ayumi Kurata· 1 shared Haruki KawaiiD· 1 shared Kanami Moriya· 1 shared Kazuho Takahashi· 1 shared Kotetsu Sasaki· 1 shared Laura C. BottiD· 1 shared Masataka KinjoiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Akira KitamuraORCID

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2 papers

Recent·Most cited

BiochemistryCellsPeer-reviewedAug 7, 2024

Spike protein of the SARS-CoV-2 omicron variant interacts with actin

Ai Fujimoto, Haruki Kawai, Rintaro Kawamura, Akira Kitamura

This study shows the Omicron variant's spike protein RBD binds more strongly to hACE2 and interacts with actin, suggesting potential changes in viral entry mechanisms.

2 citations

humanproteomics

𝕏 PostBluesky

Molecular BiologyCommunications BiologyPeer-reviewedJun 20, 2024

Hetero-oligomerization of TDP-43 carboxy-terminal fragments with cellular proteins contributes to proteotoxicity

Akira Kitamura, Ai Fujimoto, Rei Kawashima…·Masataka Kinjo

This study shows that truncated RRM in TDP-43 CTFs causes structural changes in IDR, leading to toxic hetero-oligomers and cell-nonautonomous toxicity in nematodes.

15 citations

𝕏 PostBluesky