A Statistical Method to Estimate the Population-Level Frequencies of Plasmodium falciparum Haplotypes with Pfhrp2/3 Deletions in the Presence of Mixed-Clone Infections
Loyce Kayanula, Kanika Verma, Praveen K. Bharti, Kristan Alexander Schneider
This paper introduces a statistical method to estimate Pfhrp2/3 deletion frequencies in Plasmodium falciparum infections, accounting for mixed-clone infections using neutral markers and HRP-related markers.
bioRxiv · Apr 6, 2026 · PreprintGenetics