Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5
Marek Šebesta, Karel Skubnik, William Morton, Marek Kravec, K. Linhartova, Veronika Klapstova, Jiří Nováček, Karel Kubíček, Vı́tězslav Bryja, Robert Vácha, Richard Štefl
This study identifies two mechanisms by which RECQ5 modulates RNA polymerase II transcription: attenuating elongation via the brake helix and forming a condensate scaffold matrix.
bioRxiv · Feb 5, 2025 · PreprintBiochemistry