Author

Veronika Klapstova

Masaryk UniversityORCID 0000-0003-0652-254XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:biophysical modeling· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

Marek ŠebestaiD· 2 shared Jiří NováčekiD· 1 shared Josef HouseriD· 1 shared K. LinhartovaiD· 1 shared Karel KubíčekiD· 1 shared Karel Skubnik· 1 shared Kateřina ŠedováiD· 1 shared Marek KraveciD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Marek ŠebestaORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintFeb 5, 2025

Mechanisms of transcription attenuation and condensation of RNA polymerase II by RECQ5

Marek Šebesta, Karel Skubnik, William Morton…·Richard Štefl

This study identifies two mechanisms by which RECQ5 modulates RNA polymerase II transcription: attenuating elongation via the brake helix and forming a condensate scaffold matrix.

2 citations

biophysical modelingexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintJan 22, 2025

Distinct Mechanisms of Recognition of Phosphorylated RNAPII C-Terminal Domain by BRCT Repeats of the BRCA1-BARD1 Complex: Insights from Structural and Functional Analyses

Veronika Klapstova, Kateřina Šedová, Josef Houser, Marek Šebesta

This study investigates how the BRCA1-BARD1 complex interacts with phosphorylated RNAPII CTD through BRCT repeats, revealing its role in RNAPII condensation and transcription-DNA repair coordination.

DOI 10.1101/2025.01.22.634233

proteomicsexperimental assay

𝕏 PostBluesky