Author

Karen Crawford

Cardiff University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:GWAS / association mapping· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Valentina Escott‐PriceiD· 2 shared Adam Schwartz· 1 shared Alzheimer’s Disease Neuroimaging Initiative· 1 shared Andrew J. SaykiniD· 1 shared Anthony Gamst· 1 shared Antonio F. PardiñasiD· 1 shared Arthur W. TogaiD· 1 shared Bingxin ZhaoiD· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Valentina Escott‐PriceORCID

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Author profile →

3 papers

Recent·Most cited

Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model

Núria Martín‐Flores, Marina Podpolny, Faye McLeod, Isaac Workman, Karen Crawford, Dobril K. Ivanov, Ganna Leonenko, Valentina Escott‐Price, Patricia C. Salinas

This study shows that DKK3, a Wnt antagonist elevated in Alzheimer's disease, causes synaptic loss and memory impairment, but its knockdown restores synapse integrity and memory in a mouse model.

eLife · Sep 25, 2023Peer-reviewedNeuroscience

Medical consequences of pathogenic CNVs in adults: Analysis of the UK Biobank

Karen Crawford, Matthew Bracher‐Smith, David C. Owen, Kimberley Marie Kendall, Elliott Rees, Antonio F. Pardiñas, Mark Einon, Valentina Escott‐Price, James Walters, Michael C. O’Donovan, Michael John Owen, George Kirov

This study examines the medical consequences of pathogenic CNVs in adults using UK Biobank data, finding significant associations between CNVs and various health outcomes.

Journal of Medical Genetics · Oct 20, 2018Peer-reviewedGenomics

Heritability of regional brain volumes in large-scale neuroimaging and genetic studies

Bingxin Zhao, Joseph G. Ibrahim, Yun Li, Tengfei Li, Yue Wang, Yue Shan, Ziliang Zhu, Fan Zhou, Jingwen Zhang, Chao Huang, Huiling Liao, Liuqing Yang, Paul M. Thompson, Hongtu Zhu B, Pediatric Imaging, Neurocognition and Genetics (PING), , John Hsiao

The paper examines the heritability of regional brain volumes using genetic and neuroimaging data from multiple cohorts, finding high heritability and consistent patterns across populations.

Cerebral Cortex · Jul 2, 2018Peer-reviewedGenetics