An optonanobody for reversible photoactivation of recombinant and native alpha;7 nicotinic
Maria Vangelatou, Kian Stenbolt, Sylvie Bay, Karima Medjebeur, Gabriel Aymé, Pierre J. Lafaye, Arnaud Blondel, Laurie Peverini, Alexandre Mourot, Pierre‐Jean Corringer
The paper introduces an optonanobody that reversibly photoactivates native alpha7 nicotinic receptors without genetic modification, demonstrating its effectiveness in Xenopus oocytes and hippocampal slices.
ACS Chemical Neuroscience · Jun 24, 2026Peer-reviewedNeuroscience