A Mecom—Cdk6 toggle switch governs hematopoietic stem-to-multipotent fate transitions via distinct multistable landscapes
J Rodado Martínez, Anupam Dey, MeiLu McDermott…·Adam L. MacLean
The paper models the Mecom-Cdk6 regulatory network to show how IGF signaling and self-activation shape stem cell fate transitions through multistable landscapes.