Kathrin J. Zürcher

This study shows that using a dual safety switch to eliminate neural grafts after stroke impairs functional recovery despite effective cell ablation.

This paper develops CAR-NSC therapy targeting integrin αvβ3 to improve spatial distribution and tissue engagement of transplanted cells in stroke models.

This study shows that hypoxic preconditioning of human iPSC-derived neural progenitor cells improves their survival and function after transplantation in a stroke mouse model.

This study shows that transplanting iPSC-derived neural progenitor cells improves long-term recovery after stroke in mice by promoting tissue repair and reducing neurological deficits.

This study investigates how different APOE genotypes affect human astrocytic energy metabolism, finding reduced ATP production in APOE4 astrocytes but increased mitochondrial respiration and glycolytic capacity.

This paper develops xeno-free iPSC-derived NPCs compatible with GMP for clinical use, showing long-term survival and differentiation into neurons in vivo.