Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons
Chelsey Jenna LeBlang, Maria F. Pazyra‐Murphy, Elizabeth S. Silagi, Srestha Dasgupta, Marianna Tsolias, Toussaint Miller, Veselina Petrova, Shannon Zhen, Vukasin M. Jovanovic, David Castellano, Kathryn Gerrish, Pinar Ormanoglu, Carlos A. Tristan, Ilyas Singeç, Clifford J. Woolf, , Rosalind A. Segal
This study shows that co-culturing human iPSC-derived sensory neurons with rodent satellite glia enhances their differentiation and maturation, leading to more mature phenotypes and improved disease modeling.
Stem Cell Reports · Sep 23, 2025Peer-reviewedNeuroscience