Author

Kazuto Takayasu

Tokyo Metropolitan Institute of Medical Science

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Hideya KawajiiD· 2 shared Hiroyuki SasanumaiD· 2 shared Kosuke YamazakiiD· 2 shared Tomohiro Iguchi· 2 shared Yutaka KanohiD· 2 shared Akinori EndoiD· 1 shared Ayaka Onuki· 1 shared Daichi SadatoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCell Biology

Hideya KawajiORCID

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2 papers

Recent·Most cited

BRCA2 loss triggers a downward spiral of genomic instability via ROS-dependent metabolic collapse

Hayato Hirai, Tomohiro Iguchi, Kenji Kitajima, Kosuke Yamazaki, Daichi Sadato, Kosuke Tanegashima, Yutaka Kanoh, Hiroko Masuda, Saori Wakasa, Manami Sano, Ryotaro Kawasumi, Kosei Yamada, Shintaro Yamada, Akinori Endo, Noriko Nakatsugawa, , Hiroyuki Sasanuma

This paper shows BRCA2 loss causes genomic instability through ROS-dependent metabolic collapse, highlighting the role of glutathione metabolism and PARP inhibitors in cell death.

bioRxiv · May 21, 2026 · PreprintCell Biology

Homologous recombination contributes to the repair of acetaldehyde-induced DNA damages.

Kosuke Yamazaki, Tomohiro Iguchi, Yutaka Kanoh, Kazuto Takayasu, Trinh Thi To Ngo, Ayaka Onuki, Hideya Kawaji, Shunji Oshima, Tomomasa Kanda, Hisao Masai, Hiroyuki Sasanuma

This study investigates how acetaldehyde-induced DNA damage is repaired, finding that homologous recombination and TDP1/TDP2 play critical roles in repair efficiency.

Cell Cycle · Feb 16, 2024Peer-reviewedMolecular Biology