Respiratory syncytial virus load-dependent ciliated cell dedifferentiation and downregulation of immune response genes
Kevin Berg, Sibylle Haid, Ehsan Vafadarnejad, Arnaud Carpentier, Robert Geffers, Bettina Wiegmann, Antoine‐Emmanuel Saliba, Florian Erhard, Thomas Pietschmann
This study shows RSV causes ciliated cell dedifferentiation and downregulates immune response genes, with IRF1 remaining expressed and reducing viral replication.
bioRxiv · Aug 1, 2025 · PreprintMicrobiology