Teresa Rummel

Exonuclease ISG20 inhibits human cytomegalovirus replication by inducing an innate immune defense signature

This study identifies ISG20 as an antiviral factor against HCMV by inducing an innate immune defense signature that enhances IFN production and response.

Single-cell RNA-seq using UltraMarathonRT expands the known transcriptome

This paper introduces UltraMarathonRT for scRNA-seq, revealing new transcriptomic features and demonstrating its utility in capturing additional genes and genomic elements.

Identifying Modulators of Cellular Responses by Heterogeneity-sequencing

Heterogeneity-seq identifies causal factors driving heterogeneous cellular responses by combining single-cell RNA-seq with metabolic labeling and double machine learning.

grandR: a comprehensive package for nucleotide conversion sequencing data analysis

grandR provides tools for analyzing nucleotide conversion sequencing data, including quality control, differential expression, and kinetic modeling, with a Bayesian approach for temporal RNA dynamics.