The PtdIns3P-binding protein Phafin2 escorts macropinosomes through the cortical actin cytoskeleton
Kay Oliver Schink, Kia Wee Tan, Hélène Spangenberg, Domenica Martorana, Marte Sneeggen, Coen Campsteijn, Camilla Raiborg, Harald Stenmark
This study identifies Phafin2 as a PtdIns3P-binding protein that facilitates macropinosome movement through the cortical actin cytoskeleton by regulating Filamin A.
bioRxiv · Aug 25, 2017 · PreprintCell Biology