Structure and function of the DFCP1 membrane barrier responsible for ER microdomain organization in lysosome repair
Zhicheng Cui, Karen Palacio‐Rodríguez, Eric Herrmann, Athanasios Kourniotis, Maja Radulovic, Sascha Pust, Karla Tapia, Camilla Raiborg, Gerhard Hummer, Harald Stenmark, James H. Hurley
This study determines the structure of DFCP1 and shows it forms a barrier that concentrates PI3P for lysosomal repair.
bioRxiv · Oct 23, 2026 · PreprintCell Biology