Latent cytomegalovirus disrupts NK cell responses to P. falciparum and impairs parasite control
Reena Mukhiya, Jessica R. Loughland, Nick Dooley, Zuleima Pava, Damian A. Oyong, Dean W. Andrew, Julianne Hamelink, Kiana Berry, James S. McCarthy, Bridget E. Barber, J. Alejandro Lopez, Christian R. Engwerda, Michelle J. Boyle
This study shows that latent cytomegalovirus infection reduces NK cell responses to Plasmodium falciparum and impairs parasite control by disrupting IL-12 production.
bioRxiv · Jan 28, 2026 · PreprintImmunology