Kim A Nasmyth

Multiple interactions between Scc1 and Scc2 activate cohesin’s DNA dependent ATPase and replace Pds5 during loading

The paper investigates how Scc1 and Scc2 interactions regulate cohesin's ATPase activity and displacement of Pds5 during loading.

Scc2-Mediated Loading Of Cohesin Onto Chromosomes In G1 Yeast Cells Is Insufficient To Build Cohesion During S Phase

The paper shows that Scc2 is necessary for cohesion establishment even after cohesin loading in G1 or early S phase, challenging previous findings.