Author

Sotaro Kikuchi

Nara Medical University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Ayano Fujiwara· 1 shared Bin HuiD· 1 shared Byung-Gil Lee· 1 shared Christophe Chapard· 1 shared Eeson Rajendra· 1 shared Eiichiro MoriiD· 1 shared Hiroyoshi MatsumuraiD· 1 shared Hitoki NanauraiD· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Ayano Fujiwara

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2 papers

Recent·Most cited

Toxic PR poly-dipeptides encoded by the C9orf72 repeat expansion target Kapβ2 and dysregulate phase separation of low-complexity domains

Hitoki Nanaura, Honoka Kawamukai, Ayano Fujiwara, Takeru Uehara, Mari Nakanishi, Tomo Shiota, Masaki Hibino, Yuichiro Aiba, Pattama Wiriyasermkul, Sotaro Kikuchi, Riko Nagata, Masaya Matsubayashi, Shushi Nagamori, Osami Shoji, Koichiro Ishimori, , Eiichiro Mori

This study shows that PR poly-dipeptides from C9orf72 repeat expansion bind Kapβ2 and disrupt FUS droplet melting, contributing to nucleocytoplasmic transport deficits in ALS.

bioRxiv · Oct 21, 2019 · PreprintMolecular Biology

Multiple interactions between Scc1 and Scc2 activate cohesin’s DNA dependent ATPase and replace Pds5 during loading

Naomi J Petela, Thomas G Gligoris, Jean Metson, Byung-Gil Lee, Menelaos Voulgaris, Bin Hu, Sotaro Kikuchi, Christophe Chapard, Wentao Chen, Eeson Rajendra, Madhusudhan Srinivisan, Hongtao Yu, Jan Löwe, Kim A Nasmyth

The paper investigates how Scc1 and Scc2 interactions regulate cohesin's ATPase activity and displacement of Pds5 during loading.

bioRxiv · Oct 19, 2017 · PreprintCell Biology