Autophagy Disruption Reduces mTORC1 Activation Leading to Retinal Ganglion Cell Neurodegeneration Associated with Glaucoma
Kang-Chieh Huang, Cátia Gomes, Yukihiro Shiga…·Jason S. Meyer
This study shows that autophagy disruption reduces mTORC1 activation, leading to retinal ganglion cell degeneration in glaucoma, and identifies potential therapeutic targets.