Author

Clarisse M. Fligor

Indiana University – Purdue University Indianapolis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 1

Frequent Co-Authors

Jason S. MeyeriD· 3 shared Kirstin B. VanderWall· 3 shared Kang-Chieh HuangiD· 2 shared Sailee Sham LavekariD· 2 shared Theodore CumminsiD· 2 shared Adriana Di PoloiD· 1 shared Akshayalakshmi SridhariD· 1 shared Anna R. Allsop· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Jason S. MeyerORCID

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Author profile →

3 papers

Recent·Most cited

Autophagy Disruption Reduces mTORC1 Activation Leading to Retinal Ganglion Cell Neurodegeneration Associated with Glaucoma

Kang-Chieh Huang, Cátia Gomes, Yukihiro Shiga, Nicolás Belforte, Kirstin B. VanderWall, Sailee Sham Lavekar, Clarisse M. Fligor, Jade Harkin, Shelby M. Hetzer, Shruti Patil, Adriana Di Polo, Jason S. Meyer

This study shows that autophagy disruption reduces mTORC1 activation, leading to retinal ganglion cell degeneration in glaucoma, and identifies potential therapeutic targets.

Acta Neuropathologica Communications · Oct 18, 2024Peer-reviewedNeuroscience

Retinal ganglion cells harboring the OPTN(E50K) glaucoma mutation exhibit neurodegenerative phenotypes when derived from hPSC-derived three dimensional retinal organoids

Kirstin B. VanderWall, Kang-Chieh Huang, Yanling Pan, Sailee Sham Lavekar, Clarisse M. Fligor, Anna R. Allsop, Kelly Lentsch, Pengtao Dang, Chi Zhang, Henry C. Tseng, Theodore Cummins, Jason S. Meyer

This study shows that hPSC-derived RGCs with the OPTN(E50K) mutation display neurodegenerative phenotypes, providing insights into glaucoma mechanisms.

Stem Cell Reports · Jun 11, 2020Peer-reviewedNeuroscience

Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells

Kirstin B. VanderWall, Ridhima Vij, Sarah K. Ohlemacher, Akshayalakshmi Sridhar, Clarisse M. Fligor, Elyse M. Feder, Michael Edler, Anthony J. Baucum, Theodore Cummins, Jason S. Meyer

This study shows that astrocytes accelerate the functional maturation of retinal ganglion cells derived from human pluripotent stem cells in vitro.

Stem Cell Reports · Jan 10, 2019Peer-reviewedNeuroscience