Sequential infection reprograms the immune landscape to shape future responses
Mengdi Guo, Yanis Hichem Bouzaher, Diala Abd-Rabbo, Rene Quevedo, Heidi J. Elsaesser, Wenxi Xu, Melissa Liu, Fauzia N. Izzati, Teresa Ciudad, Matthew Bianca, Kitty Liu, Joao Oliveira, Arthur Mortha, Landon J. Edgar, Tracy L. McGaha, , David G. Brooks
This study shows that sequential infections in mice remodel immune landscapes, making them more similar to human immunity and affecting future immune responses.
bioRxiv · Jul 1, 2026 · PreprintImmunology