Rene Quevedo

Sequential infection reprograms the immune landscape to shape future responses

This study shows that sequential infections in mice remodel immune landscapes, making them more similar to human immunity and affecting future immune responses.

Genome analysis and data sharing informs timing of molecular events in pancreatic neuroendocrine tumour

The paper analyzes genomic data from pancreatic neuroendocrine tumors to identify a widespread copy neutral loss-of-heterozygosity pattern linked to tumor progression and potential therapeutic targets.

Gene isoforms as expression-based biomarkers predictive of drug response in vitro

The paper identifies gene isoform-based biomarkers predictive of drug response in breast cancer using pharmacogenomic data from CCLE and GDSC.

Revisiting inconsistency in large pharmacogenomic studies

This paper reanalyzes pharmacogenomic data from GDSC and CCLE, finding continued inconsistency in drug sensitivity measures despite improved statistical methods and expanded datasets.

Assessment of pharmacogenomic agreement

The paper reanalyzes pharmacogenomic data from GDSC and CCLE, finding continued inconsistency in drug response measures despite claims of agreement.