Author

KM Butler

National Cancer Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Abdul Rouf BandayiD· 2 shared Bilal A. Lone· 2 shared Dhanusha YesudhasiD· 2 shared Abbas Yousefi-Rad· 1 shared Andrea Borghese ApoloiD· 1 shared Arup Chakraborty· 1 shared Ayşe Gökçe KeşküşiD· 1 shared Ecem Ünal· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Abdul Rouf BandayORCID

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2 papers

Recent·Most cited

APOBEC3G expression marks a TMB-high, T cell-inflamed tumor state and is associated with response to immune checkpoint blockade in multiple cancer cohorts

KM Butler, Dhanusha Yesudhas, Bilal A. Lone, Abdul Rouf Banday

This study identifies APOBEC3G as a transcriptomic marker associated with high TMB, T cell infiltration, and response to immune checkpoint blockade across multiple cancer cohorts.

bioRxiv · Jul 13, 2026 · PreprintGenomics

APOBEC3-driven neoantigen-rich cancers co-opt 1q23.3 amplification for tumor-intrinsic immune cloaking

Dhanusha Yesudhas, Bilal A. Lone, Ecem Ünal, Arup Chakraborty, Ayşe Gökçe Keşküş, Jaimie Ryou, KM Butler, Tania Colon Aquino, Abbas Yousefi-Rad, Weiming Yang, Lisa M. Miller Jenkins, Raju R. Chelluri, Elias B. A. Chandran, Vladimir Valera Romero, Salah Boudjadi, , Abdul Rouf Banday

The paper identifies a tumor-intrinsic immune-cloaking mechanism in neoantigen-rich cancers driven by APOBEC3 mutagenesis and 1q23.3 amplification, showing NECTIN4's role in suppressing immune responses.

bioRxiv · Jul 4, 2026 · PreprintCancer Biology