Author

Abbas Yousefi-Rad

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Andrea Borghese ApoloiD· 2 shared Abdul Rouf BandayiD· 1 shared Amos StemmeriD· 1 shared Arashdeep SinghiD· 1 shared Arsen OsipoviD· 1 shared Arup Chakraborty· 1 shared Ayşe Gökçe KeşküşiD· 1 shared Barliz WaissengriniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Andrea Borghese ApoloORCID

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2 papers

Recent·Most cited

APOBEC3-driven neoantigen-rich cancers co-opt 1q23.3 amplification for tumor-intrinsic immune cloaking

Dhanusha Yesudhas, Bilal A. Lone, Ecem Ünal, Arup Chakraborty, Ayşe Gökçe Keşküş, Jaimie Ryou, KM Butler, Tania Colon Aquino, Abbas Yousefi-Rad, Weiming Yang, Lisa M. Miller Jenkins, Raju R. Chelluri, Elias B. A. Chandran, Vladimir Valera Romero, Salah Boudjadi, , Abdul Rouf Banday

The paper identifies a tumor-intrinsic immune-cloaking mechanism in neoantigen-rich cancers driven by APOBEC3 mutagenesis and 1q23.3 amplification, showing NECTIN4's role in suppressing immune responses.

bioRxiv · Jul 4, 2026 · PreprintCancer Biology

Pan-cancer prediction of tumor immune activation and response to immune checkpoint blockade from tumor transcriptomics and histopathology

Sumit Mukherjee, Sumeet Patiyal, Lipika R. Pal, Keluo Yao, Tiangen Chang, Sumona Biswas, Saugato Rahman Dhruba, Amos Stemmer, Arashdeep Singh, Abbas Yousefi-Rad, Tien-Hua Chen, Binbin Wang, Denis Marino, Wonwoo Shon, Yuan Yuan, , Eytan Ruppin

This paper introduces TIME_ACT, a transcriptomic signature predicting immune checkpoint blockade response across cancers, validated using histopathology and multiple cohorts.

bioRxiv · Jun 27, 2025 · PreprintCancer Biology