GeneticsbioRxivPreprint
Targeting the homeodomain of ceramide-synthase can ameliorate insulin resistance
Christian Vera-Granda, Mariangela Sociale, Konstantin Beckschäfer…·Reinhard Bauer
The paper shows that mutations in the CerS homeodomain can either worsen or improve insulin resistance in Drosophila under high sugar diet conditions.
DOI 10.1101/2025.07.24.666377