Author

Kornelia Kuc

Evotec (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Assay:imaging· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexandra Hackmann· 1 shared Alice DrobnyiD· 1 shared Alli Leppä· 1 shared Anna LepistöiD· 1 shared Ari Ristimäki· 1 shared Bastian ZimmeriD· 1 shared Carina WollnikiD· 1 shared Carola HaapamäkiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alexandra Hackmann

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2 papers

Recent·Most cited

A human induced pluripotent stem cell-based high-throughput screening platform for teratogenicity hazard identification

Henrik Renner, Kinga Maria Wrona, Christopher Bruhn, Alice Drobny, Rachel McCannon, Fabrizia Zoppetti, Meik Henningsen, Kornelia Kuc, Carsten Jörn Beese, Carina Wollnik, Vladimir Galatenko, Alexandra Hackmann, Sandra Lubitz, Bastian Zimmer

Four-model hiPSC screen in 384-well imaging reached 83% accuracy (88% sensitivity, 75% specificity) on 130 scored compounds from a 146-compound reference set, scalable to hundreds of compounds monthly.

bioRxiv · Oct 30, 2026 · PreprintPharmacology & Toxicology✦ In-depth digest

Sustained epithelial interferon signaling modulates incomplete pathologic response in colorectal cancer

Erdoğan Pekcan Erkan, Emmi Hämäläinen, Julia Kolikova, Kornelia Kuc, Kalle Ojala, Meiju Kukkonen, Ismaïl Hermelo, Selja Koskensalo, Timo Tarvainen, Alli Leppä, Ilona Keränen, Carola Haapamäki, Essi K. Karjalainen, Monica Carpelan-Holmström, Laura Renkonen‐Sinisalo, , Toni T. Seppälä

This study identifies interferon signaling in epithelial cells as a factor contributing to incomplete response to chemotherapy in colorectal cancer, suggesting potential therapeutic targets.

bioRxiv · Mar 24, 2025 · PreprintCancer Biology