All-by-All Cytokine Receptor Pairing Network Unlocks Coding of Non-Natural T Cell States
Pingdong Tao, Kristin CY Tsui, Yang Zhao, Hua Jiang, Zinaida Good, K. Christopher García
The paper uses synthetic cytokine receptor pairings to generate novel T cell states with distinct functions, revealing how pairing orientation and STAT combinatorics influence cell fate.
bioRxiv · Aug 24, 2026 · PreprintImmunology