TRIM28 regulates pre-mRNA splicing via phosphorylation and SUMOylation networks
Vigor Matković, Cristian Prieto‐Garcia, Thorsten Mosler, Kristina Wagner, Paul W. Hotz, Felix Haidle, Joost Schimmel, Nicole Blümel, Wojciech P. Galej, Alfred C.O. Vertegaal, Michaela Müller-McNicoll, Kathi Zarnack, Stefan P Müller, Ivan Đikić
This study identifies TRIM28's role in pre-mRNA splicing through phosphorylation and SUMOylation interactions with USP39, showing its impact on alternative splicing patterns.
bioRxiv · Jul 7, 2025 · PreprintCell Biology