Wojciech P. Galej

The paper provides guidance for classifying variants in snRNA genes and introduces RNUdb, a tool to support variant annotation and classification.

EasyGrid automates cryo-EM sample preparation and quality control, improving vitrification for macromolecules and mammalian cells.

This study identifies TRIM28's role in pre-mRNA splicing through phosphorylation and SUMOylation interactions with USP39, showing its impact on alternative splicing patterns.

This paper reports cryo-EM structures of Integrator sub-complexes and identifies ZNF655 as a TF interacting with Integrator, suggesting a role in transcription regulation.

The paper presents a cryo-EM structure of the yeast P complex spliceosome post-exon ligation, revealing how the 3'-splice site is recognized through non-Watson-Crick pairing.