Author

Kye D Nichols

University of Wisconsin–Madison

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

Christian M. CapitiniiD· 1 shared Connor J Kuerbis· 1 shared Daniel D Shapiro· 1 shared Daniel F. RoadmaniD· 1 shared David J. BeebeiD· 1 shared Edwin Jason AbeliD· 1 shared Eric Nathaniel AndersoniD· 1 shared Everlyne N. Nkadori· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Christian M. CapitiniORCID

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2 papers

Recent·Most cited

CXCL13-CXCR5 Signaling in CD8⁺ T Cell Recruitment and Lymphoid Immune Organization in Clear Cell Renal Cell Carcinoma

Daniel D Shapiro, Kye D Nichols, M Violet Lee, Pavlos Msaouel, Yuanshan Li, Yang Zong, Rong Hu, Wei Huang, Karla Esbona, Toshi Kinoshita, Paz Lotan, Daniel F. Roadman, Everlyne N. Nkadori, Stephanie M. McGregor, David J. Beebe, , Edwin Jason Abel

This study identifies CXCL13-CXCR5 signaling as critical for CD8 T cell recruitment and immune organization in ccRCC, with potential as a biomarker and therapeutic target.

Cancer Immunology Immunotherapy · Jul 7, 2026Peer-reviewedCancer Biology

Axon guidance pathways modulate neurotoxicity of ALS-associated UBQLN2

Sang Hwa Kim, Kye D Nichols, Eric Nathaniel Anderson, Yining Liu, Nandini Ramesh, Weiyan Jia, Connor J Kuerbis, Mark Scalf, Lloyd M. Smith, Udai Bhan Pandey, Randal S. Tibbetts

This study identifies axon guidance pathways as modulators of UBQLN2 toxicity in ALS/FTD, showing reduced neurodegeneration with UNC5B and DCC suppression in multiple models.

eLife · Apr 11, 2023Peer-reviewedNeuroscience