Author

Weiyan Jia

University of Wisconsin–MadisonORCID 0000-0003-0899-0697Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:Drosophila· 1

Frequent Co-Authors

Lloyd M. SmithiD· 3 shared Mark Scalf· 3 shared Randal S. TibbettsiD· 3 shared Sang Hwa KimiD· 3 shared Adam S. Mastrocola· 1 shared Adenine Si-Hui KooiD· 1 shared Aditya BajajiD· 1 shared Andrew F. VoteriD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersMolecular Biology

Lloyd M. SmithORCID

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3 papers

Recent·Most cited

DNA-damage dependent isoform switching modulates RIF1 DNA repair complex assembly and phase separation

Adenine Si-Hui Koo, Weiyan Jia, Sang Hwa Kim, Mark Scalf, Claire E. Boos, Yuhong Chen, Demin Wang, Andrew F. Voter, Aditya Bajaj, Lloyd M. Smith, James L. Keck, Christopher J. Bakkenist, Lin E. Guo, Randal S. Tibbetts

This study shows DNA damage induces alternative splicing of RIF1, generating isoforms that affect DNA repair complex assembly and phase separation.

Journal of Biological Chemistry · Oct 25, 2025Peer-reviewedMolecular Biology

Axon guidance pathways modulate neurotoxicity of ALS-associated UBQLN2

Sang Hwa Kim, Kye D Nichols, Eric Nathaniel Anderson, Yining Liu, Nandini Ramesh, Weiyan Jia, Connor J Kuerbis, Mark Scalf, Lloyd M. Smith, Udai Bhan Pandey, Randal S. Tibbetts

This study identifies axon guidance pathways as modulators of UBQLN2 toxicity in ALS/FTD, showing reduced neurodegeneration with UNC5B and DCC suppression in multiple models.

eLife · Apr 11, 2023Peer-reviewedNeuroscience

Fused in sarcoma regulates DNA replication timing and progression

Weiyan Jia, Sang Hwa Kim, Mark Scalf, Peter Tonzi, Robert J. Millikin, William M. Guns, Lu Liu, Adam S. Mastrocola, Lloyd M. Smith, Tony T. Huang, Randal S. Tibbetts

This study identifies FUS's role in DNA replication timing and progression, showing its importance in genome stability and its potential contribution to disease.

Journal of Biological Chemistry · Aug 8, 2021Peer-reviewedGenomics