Author
Broad InstituteORCID 0000-0003-0860-2922Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Zinan Zhou, Lovelace J. Luquette, Guanlan Dong…·Christopher A. Walsh
The paper identifies a shared TOP1-mediated mutagenic mechanism in ALS, FTD, and AD through single-cell genomic analysis and experimental validation.
Matthew Nolan, Sandeep Aryal, I. Sandra Ndayambaje…·Clotilde Lagier‐Tourenne
The paper shows statins and mevalonate pathway inhibition increase STMN2 and ATF3, promoting neuronal regeneration in neurodegenerative disease.
Weijia Zhong, Carlo Scialò, Beatrice Gatta…·Magdalini Polymenidou
The paper investigates factors determining TDP-43 seeding outcomes in FTLD-TDP, identifying TMEM106B fibrillar core and lysosomal escape as critical drivers.
Sang Hwa Kim, Kye D Nichols, Eric Nathaniel Anderson…·Randal S. Tibbetts
This study identifies axon guidance pathways as modulators of UBQLN2 toxicity in ALS/FTD, showing reduced neurodegeneration with UNC5B and DCC suppression in multiple models.