Author

Kyle Pellegrino

University of North Carolina at Chapel HillPrimary ORCID profile (0000-0002-2917-9855 · 3 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Kyle PellegrinoiD3 papers · Howard Hughes Medical Institute

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Todd J. CoheniD· 2 shared Baggio EvangelistaiD· 1 shared Ben A. BahriD· 1 shared Carli K. OplandiD· 1 shared Diamond P. King· 1 shared Ethan Paulakonis· 1 shared Hanna TrzeciakiewicziD· 1 shared Jake McGillion-Moore· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Todd J. CohenORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Peripheral immune patterns enable robust cross-platform prediction of ALS onset and progression

Luvna Dhawka, Baggio Evangelista, Omeed K Arooji, Marie A. Iannone, Kyle Pellegrino, Rebecca Traub, Xiaoyan Li, Richard Bedlack, Rick B. Meeker, Todd J. Cohen, Natalie Stanley

The paper identifies immune coordination patterns in ALS patients and develops machine learning models to predict disease onset and progression using mass cytometry data.

bioRxiv · Aug 26, 2025 · PreprintImmunology

Synergistic MAPT mutations as a platform to uncover modifiers of tau pathogenesis

Miles R. Bryan, Michael Almeida, Kyle Pellegrino, Carli K. Opland, Ethan Paulakonis, Jake McGillion-Moore, Hanna Trzeciakiewicz, Diamond P. King, Tian Xu, Jui‐Heng Tseng, Jonathan Cummings Schisler, Nicholas G Brown, Ben A. Bahr, Todd J Cohen

This study uses synergistic MAPT mutations to create a model for tau aggregation, identifying Hsp70 as a key driver and showing its impact on neuronal function.

bioRxiv · Feb 7, 2025 · PreprintNeuroscience