Author

Carli K. Opland

University of California, Los AngelesORCID 0000-0002-8692-6028Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:protein structure· 1

Frequent Co-Authors

Andrew G. Elkins· 1 shared Ben A. BahriD· 1 shared Celine K. VuongiD· 1 shared Damon Polioudakis· 1 shared Daniel H. GeschwindiD· 1 shared Daning LuiD· 1 shared Diamond P. King· 1 shared Elizabeth K. RuzzoiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Andrew G. Elkins

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2 papers

Recent·Most cited

Synergistic MAPT mutations as a platform to uncover modifiers of tau pathogenesis

Miles R. Bryan, Michael Almeida, Kyle Pellegrino, Carli K. Opland, Ethan Paulakonis, Jake McGillion-Moore, Hanna Trzeciakiewicz, Diamond P. King, Tian Xu, Jui‐Heng Tseng, Jonathan Cummings Schisler, Nicholas G Brown, Ben A. Bahr, Todd J Cohen

This study uses synergistic MAPT mutations to create a model for tau aggregation, identifying Hsp70 as a key driver and showing its impact on neuronal function.

bioRxiv · Feb 7, 2025 · PreprintNeuroscience

A single cell transcriptomic analysis of human neocortical development

Damon Polioudakis, Luis de la Torre-Ubieta, Justin Langerman, Andrew G. Elkins, Jason L. Stein, Celine K. Vuong, Carli K. Opland, Daning Lu, William Connell, Elizabeth K. Ruzzo, Jennifer K. Lowe, Tarik Hadžić, Flora I. Hinz, Shan Sabri, William E. Lowry, , Daniel H. Geschwind

The paper defines single cell transcriptomic profiles of 40,000 human neocortical cells to identify cell types, developmental trajectories, and disease-related gene expression.

bioRxiv · Aug 28, 2018 · PreprintNeuroscience