Author

Kylie R James

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel Fernandez-Ruiz· 2 shared Anton Cozijnsen· 1 shared Ashraful HaqueiD· 1 shared Ashraful Haque· 1 shared Brendan S Crabb· 1 shared Claerwen M Jones· 1 shared Dorothee Berthold· 1 shared Fernando Souza-Fonseca-Guimaraes· 1 shared

Activity by Year

2016-2017 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Daniel Fernandez-Ruiz

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Author profile →

2 papers

Recent·Most cited

Development of a Novel CD4+ TCR Transgenic Line that Reveals a Dominant Role for CD8+ DC and CD40-Signaling in the Generation of Helper and CTL Responses to Blood Stage Malaria

Daniel Fernandez-Ruiz, Lei Shong Lau, Nazanin Ghazanfari, Claerwen M Jones, Wei Yi Ng, Gayle M Davey, Dorothee Berthold, Lauren Holz, Yu Kato, Ganchimeg Bayarsaikhan, Sanne H. Hendriks, Kylie R James, Anton Cozijnsen, Vanessa Mollard, Tania F de Koning-Ward, , William R Heath

This paper develops a CD4+ TCR transgenic mouse line to study helper and CTL responses to blood-stage malaria, showing CD8+ DC and CD40-signaling are critical for immunity.

bioRxiv · Mar 3, 2017 · PreprintImmunology

Temporal mixture modelling of single-cell RNA-seq data resolves a CD4+ T cell fate bifurcation

Tapio Lönnberg, Valentine Svensson, Kylie R James, Daniel Fernandez-Ruiz, Ismail Sebina, Ruddy Montandon, Megan S. F. Soon, Lily G Fogg, Michael J. T. Stubbington, Frederik Otzen Bagger, Max Zwiessele, Neil Lawrence, Fernando Souza-Fonseca-Guimaraes, William R. Heath, Oliver Billker, , Sarah A. Teichmann

The paper uses single-cell RNA sequencing and computational modeling to resolve CD4+ T cell fate bifurcation during Plasmodium infection, showing external influence on fate decisions by monocytes.

bioRxiv · Sep 13, 2016 · PreprintSystems Biology