Author

Kyoko Ishino

Keio University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:ChIP-seq· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Haruhiko SiomiiD· 2 shared Harumi Masuda· 2 shared Hidetoshi HasuwaiD· 2 shared Yuka W. IwasakiiD· 2 shared Atsushi ToyodaiD· 1 shared Daiki D. Horikawa· 1 shared Dominik R. LaetschiD· 1 shared Georgios KoutsovoulosiD· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersDevelopmental Biology

Haruhiko SiomiORCID

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3 papers

Recent·Most cited

Production of functional oocytes requires maternally expressed PIWI genes and piRNAs in golden hamsters

Hidetoshi Hasuwa, Yuka W. Iwasaki, Wan Kin Au Yeung, Kyoko Ishino, Harumi Masuda, Hiroyuki Sasaki, Haruhiko Siomi

This study shows that PIWI genes and piRNAs are essential for producing functional oocytes in golden hamsters, with different effects on gene expression and DNA methylation depending on the PIWI gene.

Nature Cell Biology · Sep 1, 2021Peer-reviewedDevelopmental Biology

Hamster PIWI proteins bind to piRNAs with stage-specific size variations during oocyte maturation

Kyoko Ishino, Hidetoshi Hasuwa, Jun Yoshimura, Yuka W. Iwasaki, Hidenori Nishihara, Naomi M. Seki, Takamasa Hirano, Marie Tsuchiya, Hinako Ishizaki, Harumi Masuda, Tae Kuramoto, Kuniaki Saito, Yasubumi Sakakibara, Atsushi Toyoda, Takehiko Itoh, , Haruhiko Siomi

This study investigates piRNA size variations and PIWI protein dynamics during hamster oocyte maturation, revealing stage-specific piRNA binding and transcriptional regulation in ovarian piRNA clusters.

Nucleic Acids Research · Jan 24, 2021Peer-reviewedMolecular Biology

Comparative genomics of the tardigrades Hypsibius dujardini and Ramazzottius varieornatus

Yuki Yoshida, Georgios Koutsovoulos, Dominik R. Laetsch, Lewis Stevens, Sujai Kumar, Daiki D. Horikawa, Kyoko Ishino, Shiori Komine, Takekazu Kunieda, Masaru Tomita, Mark Blaxter, Kazuharu Arakawa

The paper compares the genomes of two tardigrade species to investigate their evolutionary relationships and mechanisms of extreme survival.

PLoS Biology · Jul 27, 2017Peer-reviewedGenomics