Lewis Stevens

This study investigates the evolutionary adaptation of helminth immunomodulators by analyzing the ARI family in different nematode species and their interactions with host IL-33 and heparan sulphate.

This paper identifies three new Panagrolaimus species using genome sequencing, ultra-conserved element analysis, and morphology, supported by high-quality assemblies from long-read data.

The paper reports extreme programmed DNA elimination in Auanema rhodense during embryogenesis, revealing extensive loss of germline-specific DNA from somatic cells.

The paper presents a chromosome-scale genome assembly of Contortylenchus reversus and analyzes its population structure and host associations using genomic data from host beetles.

The paper analyzes the genomic diversity of C. tropicalis, finding geographic correlation and hyper-divergent regions linked to environmental adaptation.

The paper shows that a neo-Y chromosome emerged in nematodes with rare males, showing degeneration and male-beneficial genes, supporting its maintenance in autopseudogamy.

This study examines genome evolution in parthenogenetic nematodes, revealing chromosome fusions, rearrangements, and evidence of rare sexual reproduction events.

The paper identifies exWAGO as an ancestral regulator of LTR retrotransposons, showing it binds sRNAs from TEs and non-autonomous LTRs in extracellular forms.

This paper presents a chromosome-level genome assembly of Acrobeloides nanus, revealing genomic features and adaptations related to parthenogenesis and desiccation resistance.

The paper identifies 94 candidate genes in C. elegans linked to susceptibility to 23 environmental toxicants using genome-wide association analysis.

The paper identifies programmed DNA elimination in three Caenorhabditis species, showing it was present in their last common ancestor and later lost in some lineages.

The paper quantifies mutational sensitivity in nematode vulval development and shows how differences in sensitivity between clades explain divergent phenotypic evolution patterns.

The paper investigates Hox gene evolution and cluster organization across nematodes using high-quality genomes to explore variations in gene presence, absence, and genomic organization.

The paper improves gene models for the C. briggsae QX1410 genome through manual curation, achieving quality comparable to the well-curated AF16 strain.

This study identifies genomic signatures of benzimidazole drug resistance in Haemonchus contortus using field populations with defined treatment histories, showing the isotype-1 β-tubulin gene as the primary resistance locus.

The paper identifies natural variation in the irld gene family affecting starvation resistance in C. elegans using MIP-seq and genome-wide association.

The paper generates chromosome-level reference genomes for two C. briggsae strains, improving genomic resources for comparative genomics in the Caenorhabditis genus.

The paper identifies a new nematode species from Siberian permafrost and shows it shares cryptobiosis mechanisms with C. elegans dauer larvae.

The paper investigates intergenerational stress adaptations in C. elegans across four stress types, finding conserved physiological responses with trade-offs, but no long-term transgenerational gene expression changes.

The paper identifies three genomic regions in C. elegans associated with natural variation in macrocyclic lactone response, including two novel loci and one previously known locus.

The paper identifies a gene, sqst-5, associated with zinc resistance in C. elegans by analyzing genetic variation between strains with different zinc responses.

The paper reisolates C. bovis from Zebu cattle, sequences its genome, and analyzes its phylogenetic relationships and gene family expansions related to parasitism.

The paper describes ten new Caenorhabditis species, presents their genome sequences, and analyzes their evolutionary relationships and gene structure.

The paper investigates piRNA biogenesis in nematodes, showing that piRNA upstream motifs are derived from snRNA promoter elements and that piRNA production depends on RNA polymerase II pausing and chromatin structure.

The paper compares the genomes of two tardigrade species to investigate their evolutionary relationships and mechanisms of extreme survival.

The paper reanalyzes the genome of Hypsibius dujardini and finds no evidence for extensive horizontal gene transfer, contradicting a previous study.