Hidetoshi Hasuwa

This study identifies REFEE as a post-transcriptional regulator of repetitive RNAs that influences zygotic genome activation in mouse embryos.

This study shows that PIWI genes and piRNAs are essential for producing functional oocytes in golden hamsters, with different effects on gene expression and DNA methylation depending on the PIWI gene.

This study shows maternal diabetes causes premature senescence in the neuroepithelium, leading to neural tube defects, which can be prevented by senomorphic rapamycin.

This study investigates piRNA size variations and PIWI protein dynamics during hamster oocyte maturation, revealing stage-specific piRNA binding and transcriptional regulation in ovarian piRNA clusters.